I bumped into a problem with Oracle APEX App Builder while editing the page and been able to reproduce it on apex.oracle.com (current APEX version 23.2.4).
So, what happened was - the JavaScript code I was editing in the JavaScript popup editor overwrote item's label! This happened when I used the "Quick Edit" button in the running page and selected a page item with the editor still open.
Popup editors in the Page Designer are modal and this should prevent user from selecting another object while they are open... but with Quick Edit button this can be achieved and can lead to a problem if changes in the editor are accepted.
Other editors like PL/SQL editor or CSS editor behave in the similar way, but they are overwriting another item attributes... not necessarily the label. For example PL/SQL editor is overwriting text item's subtype, CSS editor is overwriting Template Options, File URL editor is is overwriting text item's Column attribute... HTML editor is overwriting the text item's label, similar to the JavaScript editor.
Beside those editors I mentioned, other editors might have the same behavior but I haven't tested them all.

